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Effects of Age and Heart Failure on Human Cardiac Stem Cell Function

D Cesselli, AP Beltrami... - ... of Pathology, The, 2011 - Currently, it is unknown whether defects in stem cell growth and differentiation contribute to myocardial aging and chronic heart failure (CHF), and whether a compartment of functional human cardiac stem cells (h CSCs) persists in the decompensated heart. To determine whether aging ...

Is Bitter Better? The Benefits of Chocolate for the Cardiovascular System

HE Kaynak... - Current Hypertension Reports, 2011 - Springer Background and Aims: Cocoa, particularly dark choco- late, is rich in flavonoids, and recent studies have demonstrated blood pressure lowering effects of dark chocolate. Because limited data are available on the association of chocolate consumption and the risk of coronary heart ...

26 The role of properdin in murine atherosclerosis

T Steiner, L Francescut, C Stover... - Heart, 2011 - Using a combination of bioinformatics and a luciferase reporter assay system we have identified a transcription repressor Yin Yang 1 (YY1) as a possible novel downstream target of Mst1. Cardiomyo- cytes overexpressing Mst1 were found to have an elevated level of cleaved ...

Decreased Nighttime Heart Rate Variability Is Associated With Increased Stroke Risk

Z Binici, MR Mouridsen, L Kber... - Stroke, 2011 - Am Heart Assoc Abstract Background and PurposePrediction of stroke in healthy individuals is challenging and there is a diurnal variation of stroke onset. We hypothesized that heart rate variability with a focus on nighttime heart rate variability will predict the risk of stroke in apparently ...

Relationship of agr Expression and Function with Virulence and Vancomycin Treatment Outcomes in Experimental Endocarditis due to Methicillin-Resistant ...

K Seidl, L Chen, AS Bayer, WA Hady... - Antimicrobial Agents ..., 2011 - Am Soc Microbiol ABSTRACT The accessory gene regulator (agr) locus has been shown to be important for virulence in several animal models of S. aureus infection. However, the role of agr in human infections, and specifically in antibiotic treatment is controversial. Interestingly, agr ...
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