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Central Obesity and Survival in Subjects With Coronary Artery Disease: A Systematic Review of the Literature and Collaborative Analysis With Individual Subject Data

T Coutinho, K Goel, D Correa de Sa... - Journal of the ..., 2011 - Am Coll Cardio Found Objectives: The aim of this study was to examine the association of central (waist circumference [WC] and waist-hip ratio [WHR]) and total obesity (body mass index [BMI]) measures with mortality in coronary artery disease (CAD) patients. ... Background: The question of which ...

TRAIL attenuates the development of atherosclerosis in apolipoprotein E deficient mice

V Watt, J Chamberlain, T Steiner, S Francis... - Atherosclerosis, 2011 - Elsevier We aimed to measure the effect of genetic deletion of TRAIL on atherosclerosis in a mouse model. TRAIL was mainly expressed in endothelium, smooth muscle cells and macrophages within plaques. The absence of TRAIL in chow and in fat-fed mice led to greater lesion ...

Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin

M Kanbay, LG Snchez-Lozada, M Franco... - Nephrology Dialysis ..., 2011 - ERA-EDTAAbstract Arteriolosclerosis (microvascular disease) may have a key role not only in driving salt-sensitive hypertension but also in mediating the development of chronic kidney disease, vascular dementia, stroke and coronary heart disease. In this paper, we review the ...

Cardiopulmonary Exercise Testing in Adults with Congenital Heart Disease

J Rhodes - Circulation, 2012 - Am Heart Assoc The primary task of the cardiopulmonary system is to provide blood flow and oxygen in quantities sufficient to support the individual's metabolic needs. The cardiopulmonary system is maximally stressed when an individual's metabolic rate is increased, a condition ...

Recoupling after cardiac arrest*

B Goldstein - Critical Care Medicine, 2012 - The autonomic nervous system (ANS) consists of neurons located within the central nervous system and the peripheral nervous system and which are concerned with the control of the internal environment through innervation of secretory glands and both cardiac and smooth ...
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