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Therapeutic Potential for HDAC Inhibitors in the Cardiovascular System

TA Mc Kinsey - Annual Review of Pharmacology and ..., 2011 - Annu. Rev. Pharmacol. Toxicol. 2012. 52:30319 The Annual Review of Pharmacology and Toxicology is online at This article's doi: 10.1146/annurev-pharmtox-010611-134712 Copyright c 2012 by Annual Reviews. All ...

26 The role of properdin in murine atherosclerosis

T Steiner, L Francescut, C Stover... - Heart, 2011 - Abstract Background Atherosclerosis in humans and mice has inflammatory, immune and metabolic components. Mice lacking low-density lipoprotein receptor (LDLR (−/−)) may be protected from atherogenesis by some components of the complement system. The serum ...

Multicenter trial of carperitide in patients with renal dysfunction undergoing cardiovascular surgery

K Hisatomi... - General Thoracic and Cardiovascular Surgery, 2012 - Springer Abstract Purpose The aim of this study was to evaluate the efficacy of carperitide in maintaining renal function during intraoperative and postoperative management of patients with renal dysfunction undergoing elective cardiovascular surgery. Methods The subjects ...

Lifetime Risks of Cardiovascular Disease

JD Berry, A Dyer, X Cai, DB Garside... - ... England Journal of ..., 2012 - Mass Medical Soc We conducted a meta-analysis at the individual level using data from 18 cohort studies involving a total of 257,384 black men and women and white men and women whose risk factors for cardiovascular disease were measured at the ages of 45, 55, 65, and 75 years. Blood pressure, ...

Current management of left main coronary artery disease

J Fajadet, A Chieffo - European heart journal, 2012 - Eur Soc Cardiology Abstract Coronary artery bypass surgery is considered as the gold standard treatment of unprotected left main coronary artery (ULMCA) disease. Over the last 20 years, improvement in stent technology and operators experience explained the increased number of reports ...
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