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Inhibition of IL-17A in atherosclerosis

X Cheng, S Taleb, J Wang, TT Tang, J Chen... - Atherosclerosis, 2011 - Elsevier Apo E -/- mice were treated with either rat anti-mouse IL-17A, mouse anti-mouse IL-17A or isotype-matched control antibodies for 12 weeks (n = 8-10 per group). Ldlr -/- mice were transplanted with IL-17A-deficient or wild type bone marrow (n = 8 per group). Rat anti-mouse IL-17A ...

Prevalence and Characteristics of Early Repolarization in the CASPER Registry:: Cardiac Arrest Survivors With Preserved Ejection Fraction Registry

N Derval, CS Simpson, DH Birnie... - Journal of the American ..., 2011 - Elsevier OBJECTIVES: We evaluated the prevalence and characteristics of early repolarization in patients in CASPER (Cardiac Arrest Survivors With Preserved Ejection Fraction Registry). BACKGROUND: Early repolarization has been implicated in a syndrome of polymorphic ...

Electrocardiographic and clinical predictors separating atherosclerotic sudden cardiac death from incident coronary heart disease

EZ Soliman, RJ Prineas, LD Case, G Russell... - Heart, 2011 - Objective To identify specific ECG and clinical predictors that separate atherosclerotic sudden cardiac death (SCD) from incident coronary heart disease (CHD)(non-fatal events and non-sudden death) in the combined cohorts of the Atherosclerosis Risk in ...

Treatment with selumetinib preserves cardiac function and improves survival in cardiomyopathy caused by mutation in the lamin A/C gene

A Muchir, SA Reilly, W Wu... - Cardiovascular ..., 2012 - Aims Mutations in A-type nuclear lamins gene, LMNA, lead to a dilated cardiomyopathy. We have reported abnormal activation of the extracellular signal-regulated kinase1/2 (ERK1/2) signalling in hearts from Lmna H222P/H222P mice, which develop dilated ...

Efficacy of frequent blood pressure and heart rate monitoring for early identification of bleeding following percutaneous coronary intervention

H Mert, S Seren Intepeler, N Bengu... - ... Journal of Nursing ..., 2012 - Wiley Online Library Monitoring of patients' vital signs is an important component of postpercutaneous coronary intervention (post-PCI) for bleeding early detection. This study was performed in order to identify the efficacy of frequent blood pressure (BP) and heart rate (HR) monitoring for ... [CITATION] 693: The effects of maternal caffeine intake on fetal heart rate and uterine contractions AL Tranquilli, G Buscicchio, M Piemontese... - American Journal of ..., 2012 - Elsevier [HTML]
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