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Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin

M Kanbay, LG Snchez-Lozada, M Franco... - Nephrology Dialysis ..., 2011 - ERA-EDTAArteriolosclerosis (microvascular disease) may have a key role not only in driving salt-sensitive hypertension but also in mediating the development of chronic kidney disease, vascular dementia, stroke and coronary heart disease. In this paper, we review the evidence that ...

Predicting neurological outcome after cardiac arrest

M Oddo... - Current Opinion in Critical Care, 2011 - Recent findings: Therapeutic hypothermia delays the recovery of motor responses and may render clinical evaluation unreliable. Additional modalities are required to predict prognosis after cardiac arrest and therapeutic hypothermia. Electroencephalography (EEG) can be performed ...

Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

V Bhaskar, J Yin, AM Mirza, D Phan, S Vanegas... - Atherosclerosis, 2011 - Elsevier OBJECTIVE: Atherosclerosis is a condition that is increasingly contributing to worldwide mortality through complications such as stroke and myocardial infarction. IL-1β plays multiple direct, local roles in the formation and stability of the atheroma by eliciting the ...

Molecular diagnosis of Aspergillus fumigatus endocarditis

JC Palomares, S Bernal, M Marn... - ... and infectious disease, 2011 - Elsevier A 66-year-old male with ischaemic cardiomyopathy and chronic lymphocytic leukemia developed signs of severe systemic inflammatory response syndrome. Serial blood cultures were negative and a Septi Fast test detected the presence of Aspergillus fumigatus DNA. ...

Vitamin B6 and Cardiovascular Disease

S Friso, V Lotto, R Corrocher... - Water Soluble Vitamins, 2012 - Springer While overt vitamin B6 deficiency is not a frequent finding nowadays in medical practice, evidence suggests that insufficiency of this vitamin is rather widespread in a quite large portion of the population such as the elderly or in not unusual conditions such as that of ...
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