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Myocardial Protection in Heart Surgery

RM Mentzer - Journal of Cardiovascular Pharmacology and ..., 2011 - Abstract One of the unmet clinical needs in heart surgery is the prevention of myocardial stunning and necrosis that occurs as a result of ischemia-reperfusion. Myocardial stunning, a frequent consequence after heart surgery, is characterized by a requirement for postoperative ...

Serum level of pigment epithelium-derived factor is a marker of atherosclerosis in humans

N Tahara, S Yamagishi, A Tahara, Y Nitta... - Atherosclerosis, 2011 - Elsevier OBJECTIVE: Pigment epithelium-derived factor (PEDF) could play a protective role against atherosclerosis. However, there is no clinical study to examine the relationship between serum level of PEDF and atherosclerosis in humans. METHODS/RESULTS: The study ...

Levosimendan in Two Neonates with Ischemic Heart Failure and Pulmonary Hypertension

MP De Carolis, M Piastra, I Bersani, M Pardeo... - ..., 2012 - We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart ...

TRPC channels as prospective targets in atherosclerosis: terra incognita.

G Vazquez - Frontiers in bioscience (Scholar edition), 2012 - Transient Receptor Potential Canonical (TRPC) proteins are non-selective cation channels ubiquitously expressed throughout the cardiovascular system, where they participate as Ca2+/Na+-permeable channels and/or signaling platforms in various physiological and ... [PDF]

Diagnostic Accuracy of Computed Tomography Coronary Angiography According to Pre-Test Probability of Coronary Artery Disease and Severity of Coronary Arterial ...

A Arbab-Zadeh, JM Miller, CE Rochitte... - Journal of the American ..., 2012 - Elsevier Objectives The purpose of this study was to assess the impact of patient population characteristics on accuracy by computed tomography angiography (CTA) to detect obstructive coronary artery disease (CAD). Background The ability of CTA to exclude ... [PDF]
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