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Microvascular disease and its role in the brain and cardiovascular system: a potential role for uric acid as a cardiorenal toxin

M Kanbay, LG Snchez-Lozada, M Franco... - Nephrology Dialysis ..., 2011 - ERA-EDTAAbstract Arteriolosclerosis (microvascular disease) may have a key role not only in driving salt-sensitive hypertension but also in mediating the development of chronic kidney disease, vascular dementia, stroke and coronary heart disease. In this paper, we review the ...

Cardiac MRI findings in patients with Myocarditis

Y Louvard, T Unterseeh, T Hovasse... - Journal of ..., 2011 - Background Cardiac Magnetic Resonance Imaging (CMR) is a. The recent conjoint report of the American College of Cardiology and the SCMR has classified its use as appropriate or Class A Indication in inflammatory cardiomyopathy. The aim of this study was to describe ...

End-Stage Renal Disease and Cardiomyopathy in Children: Cardiac Effects of Renal Transplantation

AK Lal, AR de Biasi, S Alexander... - ..., 2012 - Background. The occurrence and progression of cardiomyopathy is well known in patients with end-stage renal disease (ESRD). However, the feasibility of renal transplantation in the setting of cardiac dysfunction and the effect of renal transplantation on this progression ...

Cardiopulmonary Exercise Testing in Adults with Congenital Heart Disease

J Rhodes - Circulation, 2012 - Am Heart Assoc The primary task of the cardiopulmonary system is to provide blood flow and oxygen in quantities sufficient to support the individual's metabolic needs. The cardiopulmonary system is maximally stressed when an individual's metabolic rate is increased, a condition ...

Pharmacological Suppression of Hepcidin Increases Macrophage Cholesterol Efflux and Reduces Foam Cell Formation and Atherosclerosis

O Saeed, F Otsuka, R Polavarapu... - ... and Vascular Biology, 2012 - Am Heart Assoc ObjectiveWe recently reported that lowering of macrophage free intracellular iron increases expression of cholesterol efflux transporters ABCA1 and ABCG1 by reducing generation of reactive oxygen species. In this study, we explored whether reducing ...
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