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Association of incident cardiovascular disease with progression of sleep-disordered breathing

HA Chami, HE Resnick, SF Quan... - Circulation, 2011 - Am Heart Assoc Methods and Results A total of 2721 Sleep Heart Health Study participants (mean age 62, standard deviation=10 years; 57% women; 23% minority) without CVD at baseline underwent 2 polysomnograms 5 years apart. Incident CVD events, including myocardial infarction, ...

Oncostatin M is expressed in atherosclerotic lesions: A role for Oncostatin M in the pathogenesis of atherosclerosis.

A Albasanz-Puig, J Murray, M Preusch, D Coan... - Atherosclerosis, 2011 - Elsevier Chronic inflammation plays a pivotal role in the development and progression of atherosclerosis. The inflammatory response is mediated by cytokines. The aim of this study was to determine if Oncostatin M (OSM), a monocyte and T-lymphocyte specific cytokine is ...

... -Binding Globulin, But Not Testosterone, Is Associated Prospectively and Independently With Incident Metabolic Syndrome in Men: The Framingham Heart Study.

S Bhasin, GK Jasjua, M Pencina... - Diabetes ..., 2011 - OBJECTIVEThe association between total testosterone and metabolic syndrome has prompted speculation that low testosterone contributes to the pathophysiology of metabolic syndrome in men. We determined whether testosterone or sex hormone-binding globulin (SHBG) is ... [CITATION] D-Dimer and the Risk of Cardiovascular Disease: The Framingham Heart Study E Shaw, J Massaro, D Levy, C O'Donnell... - Heart, Lung and ..., 2011 - Elsevier

Efficacy of NZ2114, a Novel Plectasin-Derived Cationic Antimicrobial Peptide Antibiotic, in Experimental Endocarditis Due to Methicillin-Resistant Staphylococcus ...

YQ Xiong, WA Hady, A Deslandes... - Antimicrobial Agents ..., 2011 - Am Soc Microbiol ABSTRACT Cationic antimicrobial peptides (CAPs) play important roles in host immune defenses. Plectasin is a defensin-like CAP isolated from the saprophytic fungus Pseudoplectania nigrella. NZ2114 is a novel variant of plectasin with potent activity ...

Turning 18 with congenital heart disease: prediction of infective endocarditis based on a large population

CL Verheugt, CSPM Uiterwaal... - European heart ..., 2011 - Eur Soc Cardiology Aims The risk of infective endocarditis (IE) in adults with congenital heart disease is known to be increased, yet empirical risk estimates are lacking. We sought to predict the occurrence of IE in patients with congenital heart disease at the transition from childhood into ...
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