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Apolipoprotein E genotypes, circulating C-reactive protein and angiographic coronary artery disease (The Ludwigshafen Risk and Cardiovascular Health Study)

TB Grammer, MM Hoffmann, W Renner, ME Kleber... - Atherosclerosis, 2011 - Elsevier C-reactive protein (CRP) has been implicated in the development of atherosclerosis. The genetic polymorphism of apolipoprotein (apo) E is associated with the concentration of CRP. We analyzed the association between the apo E genotype, CRP and angiographic coronary artery ...

Seizures After Open Heart Surgery: Comparison of [epsilon]-Aminocaproic Acid and Tranexamic Acid

K Martin, J Knorr, T Breuer, R Gertler... - ... of Cardiothoracic and ..., 2011 - Elsevier OBJECTIVE: Although the lysine analogs tranexamic acid (TXA) and aminocaproic acid (EACA) are used widely for antifibrinolytic therapy in cardiac surgery, relatively little research has been performed on their safety profiles, especially in the setting of cardiac surgery. ...

Relationship between hemodynamics and atherosclerosis in aortic arches of apolipoprotein E-null mice on 129S6/SvEvTac and C57BL/6J genetic backgrounds

H Tomita, J Hagaman, MH Friedman... - Atherosclerosis, 2011 - Elsevier Objective We investigated the relationships between hemodynamics and differential plaque development at the aortic arch of apolipoprotein E (apo E)-null mice on 129S6/Sv Ev Tac (129) and C57BL/6 J (B6) genetic backgrounds. Methods Mean flow velocities at the ...

Comparative long‐term efficacy and safety of drug‐eluting stent versus coronary artery bypass grafting in ostial left main coronary artery disease

SW Lee, SH Kim, SO Kim, S Han... - Catheterization and ..., 2012 - Wiley Online Library Background: To date, drug-eluting stent (DES) implantation has not been compared with coronary artery bypass grafting (CABG) for ostial left main coronary artery (LMCA) lesions. Methods: Of the 263 patients in the MAIN-COMPARE registry with ostial LMCA stenosis, ...

Subcellular Structures and Function of Myocytes Impaired During Heart Failure Are Restored by Cardiac Resynchronization Therapy

FB Sachse, NS Torres, E Savio-Galimberti... - Circulation ..., 2012 - Am Heart Assoc Abstract Rationale: Cardiac resynchronization therapy (CRT) is an established treatment for patients with chronic heart failure. However, CRT-associated structural and functional remodeling at cellular and subcellular levels is only partly understood. Objective: To ... [PDF]
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