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Mitogen-Activated Protein Kinase Inhibitors Improve Heart Function and Prevent Fibrosis in Cardiomyopathy Caused by Mutation in Lamin A/C Gene

W Wu, A Muchir, J Shan, G Bonne... - Circulation, 2011 - Am Heart Assoc Background Mutations in the lamin A/C gene, LMNA, can cause dilated cardiomyopathy. We have shown abnormal activation of the extracellular signal-regulated kinase (ERK) and the c-jun N-terminal kinase (JNK) branches of the mitogen-activated protein kinase signaling ...

Açaí Juice Attenuates Atherosclerosis in ApoE Deficient Mice through Antioxidant and Anti-inflammatory Activities 1-2

C Xie, J Kang, R Burris, ME Ferguson, AG Schauss... - Atherosclerosis, 2011 - Elsevier Apo E -/− mice were fed AIN-93G diet (CD) or CD formulated to contain 5% freeze-dried aa juice powder (AJ) for 20 weeks. The mean lesion areas in the aorta for apo E -/− mice fed AJ were 58% less (P < 0.001) compared to that for CD fed mice. HDL-cholesterol was higher in AJ ...

Positron Emission Tomography/Computed Tomography for the Diagnosis of Endocarditis in Patients With Pulmonic Stented Valve/Pulmonic Stent

I Yedidya, GY Stein, M Vaturi... - The Annals of ..., 2011 - Soc Thorac Surgeons Percutaneous pulmonic valve and pulmonic stent implantation have become a well-established treatment for recurrent pulmonic stenosis or insufficiency in patients with repaired congenital heart disease. Late endocarditis is seldom reported, but its diagnosis might be ...

Impact of excess weight on the relationship between blood pressure and cardiovascular disease; The Asia Pacific Cohort Studies collaboration (abstract and poster ...

R Tsukinoki, Y Murakami, R Huxley... - ... of Epidemiology and ..., 2011 - Item Metadata (Short). Title, Impact of excess weight on the relationship between blood pressure and cardiovascular disease; The Asia Pacific Cohort Studies collaboration (abstract and poster presentation for IEA World Congress of Epidemiology, 7-11 August 2011, Edinburgh). ...

A low pulse pressure predicts mortality in subjects with heart failure after an acute myocardial infarction: a post-hoc analysis of the CAPRICORN study

CJ Petrie, AA Voors, M Robertson... - Clinical Research in ..., 2011 - Springer Abstract Background In patients with cardiovascular disease, a high pulse pressure is related to an increased risk of cardiovascular events but in patients with advanced heart failure, a low pulse pressure is predictive of adverse (cardiovascular) events. Aim We ...
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