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Statins exert differential effects on angiotensin II-induced atherosclerosis, but no benefit for abdominal aortic aneurysms

X Xie, W Chen, Y Wang, S Zhang, H Bi, B Hong... - Atherosclerosis, 2011 - Elsevier OBJECTIVE: Statins reduce atherosclerosis, but it is controversial whether they suppress abdominal aortic aneurysm (AAA) expansion. We hypothesized that statins (rosuvastatin and atorvastatin) would attenuate angiotensin II (Ang II)-induced atherosclerosis and AAA. ...

... wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling

L Conde, S Bevan, M Sitzer, N Klopp, T Illig... - Atherosclerosis, 2011 - Elsevier Recent genome-wide association studies (GWAS) have identified associations with myocardial infarction and coronary artery disease (CAD), but the mechanisms underlying these associations remain largely unclear. Carotid intima-media thickness (IMT) is a measure of early arterial ...

Decreased neuroautonomic complexity in men during an acute major depressive episode: analysis of heart rate dynamics

SJJ Leistedt, P Linkowski, JP Lanquart... - Translational ..., 2011 - Abstract Major depression affects multiple physiologic systems. Therefore, analysis of signals that reflect integrated function may be useful in probing dynamical changes in this syndrome. Increasing evidence supports the conceptual framework that complex ... [HTML]

Antiviral effects of interferon-β are enhanced in the absence of the translational suppressor 4E-BP1 in myocarditis induced by Coxsackievirus B3

JD Burke, N Sonenberg, LC Platanias... - Antiviral therapy, 2011 - Background: Viral myocarditis is most frequently associated with infection by Coxsackievirus B3 (CVB3). Interferon (IFN)-β therapy has been studied and could reduce virally induced tissue damage and improve heart function. Methods: In the present study we have ...

Physiology of cardiovascular system. Functional characteristics of myocardium.

ОА Обухова, ОА Обухова... - 2012 - of cardiovascular system. Functional characteristics of myocardium. ... The Blood Vessels. The cardiovascular system has three types of blood vessels: Arteries (and arterioles) carry blood away from the heart; Capillaries where nutrient and gas exchange occur; ...
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