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... vivo evaluation of (R)-and (S)-[carbon-11] rolipram for imaging cardiac phosphodiesterase-4 enzymes: Characterization and applications in rat models of heart failure
M Kenk - 2012 - Abstract: Heart failure is associated with alterations in noradrenergic 3', 5'-cyclic adenosine monophosphate (c AMP)-mediated phosphodiesterase 4 (PDE4) signaling. Comprehensive study of the intracellular mechanism involved in the progression of heart failure is ...
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... vivo evaluation of (R)-and (S)-[carbon-11] rolipram for imaging cardiac phosphodiesterase-4 enzymes: Characterization and applications in rat models of heart failure |
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