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Body Weight in Early and Mid-Adulthood in Relation to Subsequent Coronary Heart Disease Mortality: 80-Year Follow-up in the Harvard Alumni Study
L Gray, I Lee, HD Sesso... - Archives of Internal ..., 2011 - Am Med Assoc Results A maximum of 82.5 years of follow-up (median, 56.4 years) gave rise to 2025 CHD deaths in the 18 995 men. The correlation between BMI in early adulthood and middle age was moderate (r= 0.49; P<. 001). Men who were obese in early adulthood had nearly ...
The Harvard Alumni Health Study is a cohort study of men who had a routine medical examination as undergraduates at Harvard University, Cambridge, Massachusetts, between 1916 and 1950.7 Measurements of height, weight, and blood pressure were made, and students responded to enquiries regarding smoking habits7 ; details on physical activity were ascertained from university records.6 Questionnaires mailed to surviving alumni in either 1962 or 1966 included questions about height, weight, lifestyle habits, and medical history; a high level of agreement has been shown between these responses and direct measurements.7 Harvard Alumni Office listings were used to identify decedents, and copies of official death certificates were obtained with 99% coverage.8 Deaths from CHD were coded according to the seventh revision of the International Classification of Disease (ICD) (code 420).
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Body Weight in Early and Mid-Adulthood in Relation to Subsequent Coronary Heart Disease Mortality: 80-Year Follow-up in the Harvard Alumni Study |
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