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Altitude, life expectancy and mortality from ischaemic heart disease, stroke, COPD and cancers: national population-based analysis of US counties
M Ezzati, MEM Horwitz, DSK Thomas... - ... of Epidemiology and ..., 2011 - Contributors ME, DSKT, CJLM and BH designed the study. MEMH and ABF analysed county
mortality, socio-demographic and solar radiation data; DSKT and TC analysed county elevation
data. ME and CJLM designed the statistical analysis of the elevationoutcome ...
Results Counties above 1500 m had longer life expectancies than those within 100 m of sea level by 1.2–3.6 years for men and 0.5–2.5 years for women. The association between altitude and life expectancy became non-significant for women and non-significant or negative for men in multivariate analysis. After adjustment, altitude had a beneficial association with IHD mortality and harmful association with COPD, with a dose–response relationship. IHD mortality above 1000 m was 4–14 per 10 000 people lower than within 100 m of sea level; COPD mortality was higher by 3–4 per 10 000. The adjusted associations for stroke and cancers were not statistically significant.
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Altitude, life expectancy and mortality from ischaemic heart disease, stroke, COPD and cancers: national population-based analysis of US counties |
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