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Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

V Bhaskar, J Yin, AM Mirza, D Phan, S Vanegas... - Atherosclerosis, 2011 - Elsevier Atherosclerosis is a condition that is increasingly contributing to worldwide mortality through complications such as stroke and myocardial infarction. IL-1β plays multiple direct, local roles in the formation and stability of the atheroma by eliciting the production of additional ...

Effects of Pacing Site on Global and Regional Left Ventricular Function in the Setting of Dyssynchronous Heart Failure

EJ Howard - 2012 - Abstract: Regional estimates of left ventricular function are important for understanding normal cardiac function. In the presence of electrical dyssynchrony and heart failure, substantial remodeling of left ventricular geometry and cellular function occurs, resulting in ...

Cardiovascular health, risks and diseases in contemporary China

TO Cheng - International Journal of Cardiology, 2012 - Corresponding Author Information Department of Medicine, The George Washington University Medical Center, 2150 Pennsylvania Avenue, NW, Washington, DC 20037, United States. Tel.:+ 1 202 741 2426; fax:+ 1 202 741 2324.

Posttraumatic growth in coronary artery disease outpatients: Relationship to degree of trauma and health service use

YW Leung, DA Alter, PL Prior, DE Stewart... - Journal of ..., 2012 - Elsevier Objectives Posttraumatic growth (PTG) is frequently reported after the strike of a serious medical illness. The current study sought to: 1) assess the relationship between degree of cardiac threat and PTG one-year post-hospitalization; and 2) to explore the association ...

Trends in Use of Implantable Cardioverter Defibrillator Therapy Among Patients Hospitalized for Heart Failure: Have the Previously Observed Sex and Racial ...

SM Al-Khatib, AS Hellkamp, AF Hernandez... - Circulation, 2012 - Am Heart Assoc BackgroundPrior studies have demonstrated low utilization of primary prevention implantable cardioverter defibrillators (ICDs), particularly among women and blacks. The degree to which the overall use of ICD therapy and disparities in use have changed is ...
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