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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

H Schunkert, IR Knig, S Kathiresan, MP Reilly... - Nature genetics, 2011 - We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by genotyping of top association signals in 56,682 additional individuals. This ...

How does feeling blue make the heart grow sicker? Examining the role of the metabolic syndrome in the relationship between depression and coronary heart disease

JE Stevenson - 2012 - Abstract: The aim of the present study was to utilize a structural equation modeling (SEM) approach to simultaneously examine the relationship among depressive symptoms measured by the Center for Epidemiologic Studies Depression Scale (CES-D), the ...

p53-Induced Adipose Tissue Inflammation Is Critically Involved in the Development of Insulin Resistance in Heart Failure

I Shimizu, Y Yoshida, T Katsuno, K Tateno... - Cell Metabolism, 2012 - Elsevier Summary Several clinical studies have shown that insulin resistance is prevalent among patients with heart failure, but the underlying mechanisms have not been fully elucidated. Here, we report a mechanism of insulin resistance associated with heart failure that ...

Association of Body Mass Index With Peripheral Arterial Disease in Older Adults: The Cardiovascular Health Study

JH Ix, ML Biggs... - Journal of Vascular Surgery, 2012 - No abstract is available. To read the body of this article, please view the Full Text online. ... 2012 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved. ... Visit Sci Verse Science Direct to see if you have access via your institution. ... Advertisements on this site ...

... to the Inconsistency Between Plasma B-type Natriuretic Peptide Levels and the Severity of Pulmonary Congestion on Chest X-rays in the Diagnosis of Heart Failure.

T Nakane, M Kawai, K Komukai... - Internal medicine ( ..., 2012 - Objective Chest X-rays and plasma B-type natriuretic peptide (BNP) levels are useful for diagnosing congestive heart failure. However, the relationship between plasma BNP levels and pulmonary congestion on chest X-rays often seems inconsistent. Extracardiac factors ...
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