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Recombinant factor VIIa (NovoSeven RT) use in high risk cardiac surgery.

AJ Chapman, AL Blount, AT Davis... - European journal of ..., 2011 - Objective: The use of recombinant factor VIIa (r FVIIa) (Novo Seven RT()) to establish hemostasis during massive perioperative bleeding in cardiac surgery has been explored in several retrospective studies. While early results are promising, a paucity of data leaves many questions about ...

... an intravenous lipid emulsion containing fish oil (eicosapentaenoic and docosahexaenoic acid) decreases inflammatory markers after open-heart surgery in infants: A ...

BMK Larsen, LA Goonewardene, AR Joffe... - Clinical Nutrition, 2011 - Elsevier Methods Thirty-two infants (402.3 weeks gestational age; 10.6 days at time of surgery) undergoing open-heart surgery with cardiopulmonary bypass were randomized to receive an intravenous lipid emulsion with (treatment) or without (control) eicosapentaenoic and ...

Can geriatricians improve inpatient heart failure care? Time for a heart to heart

J Baxter... - Age and Ageing, 2012 - Br Geriatrics Soc Chronic heart failure (CHF) due to left ventricular systolic dysfunction is a disease of old age. Incidence and prevalence increases with age, with the mean age of diagnosis being 76 years [1, 2]. There is now an extensive evidence base to help guide diagnosis and ...

Myocardial oxidative stress in patients with active infective endocarditis

S Ostrowski, M Kasielski, J Kordiak... - International Journal of ..., 2012 - Elsevier Background Infective endocarditis (IE) induces the rise of pro-inflammatory cytokines. Some of them can stimulate oxidants production in myocardium with subsequent peroxidative damage to various biomolecules. We compared indices of oxidative stress: H 2 O 2, ... [PDF]

Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1

X Yang, Q Li, X Lin, Y Ma, X Yue, Z Tao... - The FASEB Journal, 2012 - FASEBAbstract We have previously found that in failing human hearts, Rho-associated coiled-coil protein kinase 1 (ROCK1) is processed by caspase-3 into an active isoform, ROCKΔ1. The purpose of the current investigation was to elucidate the pathological consequences of ...
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