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Effects of age and heart failure on human cardiac stem cell function.

D Cesselli, AP Beltrami, F D'Aurizio... - The American journal ..., 2011 - Currently, it is unknown whether defects in stem cell growth and differentiation contribute to myocardial aging and chronic heart failure (CHF), and whether a compartment of functional human cardiac stem cells (h CSCs) persists in the decompensated heart. To determine whether aging ...

Percutaneous Approaches to Valvular Heart Disease After Previous Cardiac Surgery

JM Stulak... - Redo Cardiac Surgery in Adults, 2012 - Springer While open surgical correction is the best treatment for most patients with valvular heart disease, there have been recent technical advances that permit percutaneous approaches to valve replacement and valve repair in selected circumstances. The most widely ... [CITATION] Does aortic stiffness improve the prediction of coronary heart disease in elderly? The Rotterdam Study GC Verwoert, SE Elias-Smale, D Rizopoulos... - Journal of Human ..., 2012

The combination of carotid and lower extremity ultrasonography increases the detection of atherosclerosis in type 2 diabetes patients

L Li, H Yu, J Zhu, X Wu, F Liu, F Zhang... - Journal of Diabetes and ..., 2012 - Elsevier Objective To evaluate the prevalence of atherosclerosis detected by both carotid and lower extremity ultrasonography in hospitalized Chinese type 2 diabetic patients and to examine whether plaque formation in the carotid arteries could be an indicator of generalized ...

The obesity paradox in elderly patients with heart failure: Analysis of nutritional status

A Casas-Vara, F Santolaria... - Nutrition, 2012 - Elsevier Objective The obesity paradox refers to the improved survival of obese compared with non-obese elderly or diseased patients for reasons that are not clear. To assess the relative roles of fat and other factors in this improved survival, we analyzed the prognostic value of ...

Comparison of the IKr blockers moxifloxacin, dofetilide and E‐4031 in five screening models of pro‐arrhythmia reveals lack of specificity of isolated cardiomyocytes

L Nalos, R Varkevisser, MKB Jonsson... - British Journal of ..., 2012 - Wiley Online Library BACKGROUND AND PURPOSE Drug development requires the testing of new chemical entities for adverse effects. For cardiac safety screening, improved assays are urgently needed. Isolated adult cardiomyocytes (CM) and human embryonic stem cell-derived ... [CITATION] 249 Acute pericardial effusion following atrial fibrillation ablation: Characteristics and relationship with arrhythmia recurrences F Sebag, N Lellouche, N Elbaz, E Teiger... - Archives of ..., 2012 - Elsevier
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