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W Wu, A Muchir, J Shan, G Bonne... - Circulation, 2011 - Am Heart Assoc Background Mutations in the lamin A/C gene, LMNA, can cause dilated cardiomyopathy. We
have shown abnormal activation of the extracellular signal-regulated kinase (ERK) and the
c-jun N-terminal kinase (JNK) branches of the mitogen-activated protein kinase signaling ...
TB Grammer, MM Hoffmann, W Renner, ME Kleber... - Atherosclerosis, 2011 - Elsevier C-reactive protein (CRP) has been implicated in the development of atherosclerosis. The genetic
polymorphism of apolipoprotein (apo) E is associated with the concentration of CRP. We analyzed
the association between the apo E genotype, CRP and angiographic coronary artery ...
A Stangherlin... - American Journal of Physiology- ..., 2011 - Am Physiological Soc Abstract Phosphodiesterases (PDEs) are key enzymes in the c AMP signaling cascade. They convert c AMP in its inactive form 5'-AMP and critically regulate the intensity and the duration of c AMP-mediated signals. Multiple isoforms exist that possess different intracellular ...
BM Kaess, A Pedley, JM Massaro... - Journal of Clinical ..., 2011 - Endocrine Soc Background: Visceral adiposity is associated with metabolic risk. Given that angiogenesis is a key feature of adipogenesis, variation in the association of levels of circulating vascular growth factors (and their soluble receptors) with distinct body fat compartments may ...
RD Lopes, RH Mehta, GE Hafley, JB Williams... - Circulation, 2012 - Am Heart Assoc BackgroundVein graft failure (VGF) is common following coronary artery bypass graft (CABG) surgery, but its relationship with long-term clinical outcomes is unknown. In this retrospective analysis, we examined the relationship between VGF, assessed by coronary ...
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