Heart Care Info - Heart Disease Prevention & Treatment

Extent of wall motion abnormalities with cardiovascular magnetic resonance imaging overestimates the degree of coronary artery disease in patients with ischemic ...

T Danilov, A Mignatti, RP Lim, L Axel... - Journal of ..., 2011 - ... PMCID: PMC3106552. Copyright 2011 Danilov et al; licensee Bio Med Central Ltd. Extent of wall motion abnormalities with cardiovascular magnetic resonance imaging overestimates the degree of coronary artery disease in patients with ischemic cardiomyopathy. ...

Of 901 segments, 638 (71%) had WMA, with severe WMA in 378 (42%). In contrast, only 340 (38%) had LGE, including 233 (24%) with >50% transmural LGE, consistent with larger extent of WMA compared to LGE. No significant correlations were found between segments with any WMA and >50% transmural LGE (r= 0.05, p=0.71.). Of the 53 patients with ischemic CMP by LGE-CMR, 47 patients (89%) had documented coronary artery disease by angiography. There was no significant correlation between number of vessels with severe stenoses (>70%) and any WMA (r=0.19, p=0.18). Additionally, the number of segments with evidence of any WMA was more extensive than number of segments supplied by severe stenoses.