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Overexpression of the Multidrug Resistance Protein-4 Transporter in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Cause of Aspirin Resistance?
JW Eikelboom... - Journal of the American ..., 2011 - Am Coll Cardio Found Millions of people take aspirin every day for the prevention of atherothrombotic cardiovascular events. Aspirin inhibits thrombus formation by irreversibly inactivating the cyclooxygenase (COX)-1 enzyme in platelets, thereby blocking platelet production of ...
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Overexpression of the Multidrug Resistance Protein-4 Transporter in Patients Undergoing Coronary Artery Bypass Graft Surgery: A Cause of Aspirin Resistance? |
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