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Free fatty acids are associated with insulin resistance but not coronary artery atherosclerosis in rheumatoid arthritis

MJ Ormseth, LL Swift, S Fazio, MRF Linton... - Atherosclerosis, 2011 - Elsevier Abstract Background Free fatty acids (FFAs) affect insulin signaling and are implicated in the pathogenesis of insulin resistance and atherosclerosis. Inflammatory cytokines such as interleukin-6 (IL-6) increase lipolysis and thus levels of FFAs. We hypothesized that ...

Shared genetic architecture in the relationship between adult stature and subclinical coronary artery atherosclerosis

AE Cassidy-Bushrow, LF Bielak, PF Sheedy... - Atherosclerosis, 2011 - Elsevier Background Short stature is associated with increased risk of coronary heart disease (CHD); although the mechanisms for this relationship are unknown, shared genetic factors have been proposed. Subclinical atherosclerosis, measured by coronary artery calcification ( ...

Effect of a family heart health program on stage of change constructs of exercise and leisure time exercise in family members of patients with heart disease

J Kocourek - 2011 - Abstract: The purpose of this study was to assess the effect of a family heart health program on stage of change constructs for exercise behaviour and self-reported leisure time exercise in family members of patients with coronary heart disease (CHD).

Genomewide Association Studies in Cardiovascular Disease—An Update 2011

T Zeller, S Blankenberg... - Clinical Chemistry, 2012 - Am Assoc Clin Chem BACKGROUND: Genomewide association studies have led to an enormous boost in the identification of susceptibility genes for cardiovascular diseases. This review aims to summarize the most important findings of recent years.

Preoperative Prediction of Non-Home Discharge: A Strategy to Reduce Resource Use after Cardiac Surgery

G Pattakos, DR Johnston, PL Houghtaling... - Journal of the American ..., 2012 - Elsevier BACKGROUND: Patients requiring discharge to a continuing care facility after cardiac surgery (non-home discharge) frequently have prolonged hospital stays while arrangements are made for posthospital care. We hypothesized that preoperatively identifying patients ...
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