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Arrhythmia Formation in Subclinical (“Silent”) Long QT Syndrome Requires Multiple Insults: Quantitative Mechanistic Study Using the KCNQ1 Mutation Q357R as ...

T O'Hara... - Heart Rhythm, 2011 - Elsevier In subclinical, or silentlong QT syndrome (LQTS), the QT interval is normal under basal conditions. The hypothesis thatinsults to the repolarization reserve may cause arrhythmias insilent mutation carriers, but not in non-carriers, has been proposed as a general principle, yet ...

Removal of respiratory influences from heart rate variability in stress monitoring

J Choi... - Sensors Journal, IEEE, 2011 - Abstract This article addresses a major weakness of traditional heart-rate-variability (HRV) analysis for the purpose of monitoring stress: sensitivity to respiratory influences. To address this issue, a linear system-identification model of the cardio-respiratory system using ...

Health-promoting and health-damaging neighbourhood resources and coronary heart disease: a follow-up study of 2 165 000 people

N Kawakami, X Li... - Journal of Epidemiology and ..., 2011 - ... the Scottish Heart Health Study. J Epidemiol Community Health 1996;50:5706. [Abstract/FREE Full text]. ↵: Smith GD,; Hart C,; Watt G,; et al. . Individual social class, area-based deprivation, cardiovascular disease risk factors, and mortality: the Renfrew and Paisley Study. ...

Relationship of agr Expression and Function with Virulence and Vancomycin Treatment Outcomes in Experimental Endocarditis due to Methicillin-Resistant ...

K Seidl, L Chen, AS Bayer, WA Hady... - Antimicrobial Agents ..., 2011 - Am Soc Microbiol ABSTRACT The accessory gene regulator (agr) locus has been shown to be important for virulence in several animal models of S. aureus infection. However, the role of agr in human infections, and specifically in antibiotic treatment is controversial. Interestingly, agr ...

Antiviral Activity of Coxsackievirus B3 3C Protease Inhibitor in Experimental Murine Myocarditis

SH Yun, WG Lee, YC Kim, ES Ju... - Journal of Infectious ..., 2012 - Background. We investigated the efficacy of a 3C protease inhibitor (3CPI) in a murine coxsackievirus B3 (CVB3) myocarditis model. CVB3 is a primary cause of viral myocarditis. The CVB3 genome encodes a single polyprotein that undergoes a series of proteolytic ... [PDF]
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