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Roles of guanylyl cyclase-A signaling in the cardiovascular system 1 1 This paper is one of a selection of papers published in the Special Issue entitled The endocrine ...
Y Saito, I Kishimoto... - Canadian Journal of ..., 2011 - NRC Research Press Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are cardiac hormones synthesized in and secreted from the heart. ANP and BNP bind the common receptor guanylyl cyclase-A (GC-A) and possess biological actions. Based on their diuretic, ...
Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are cardiac hormones synthesized in and secreted from the heart. ANP and BNP bind the common receptor guanylyl cyclase-A (GC-A) and possess biological actions. Based on their diuretic, natriuretic, and vasodilating activities, they are now widely used as therapeutic agents for heart failure. Roles of endogenous ANP and BNP have been investigated using mice lacking the gene encoding GC-A. Here we describe the recent understanding of roles of GC-A in the cardiovascular system.
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Roles of guanylyl cyclase-A signaling in the cardiovascular system 1 1 This paper is one of a selection of papers published in the Special Issue entitled The endocrine ... |
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