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The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established, cardiovascular health

The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established


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PCH Hollman, A Cassidy, B Comte... - The Journal of ..., 2011 - Am Soc Nutrition Abstract Human studies provide evidence for beneficial effects of polyphenol-rich foods on cardiovascular health. The antioxidant activity of polyphenols potentially explains these effects, but is the antioxidant activity a reliable predictor for these effects? An International ...

↵3 Author disclosures: M. Richelle is employed by Nestle and S. Vidry is employed by ILSI Europe. Authors with academic affiliations may have received an honorarium from ILSI Europe for their participation in this publication and/or reimbursement of their travel and accommodation costs for attending the related meetings.

↵1 Published in a supplement to The Journal of Nutrition, and based on work carried out by an ILSI Europe Functional Foods Expert Group “Application of PASSCLAIM Criteria on Polyphenols Antioxidant Activity.” The supplement coordinators for this supplement were Maria Skarp and Alessandro Chiodini. Supplement Coordinator disclosures: Maria Skarp was employed by ILSI Europe at the time of the publication, and Alessandro Chiodini is employed by ILSI Europe. The supplement is the responsibility of the Guest Editor to whom the Editor of The Journal of Nutrition has delegated supervision of both technical conformity to the published regulations of The Journal of Nutrition and general oversight of the scientific merit of each article. The Guest Editor for this supplement was Maria Luz Fernandez. Guest Editor disclosure: Maria Luz Fernandez had no conflicts to declare. Publication costs for this supplement were defrayed in part by the payment of page charges. This publication must therefore be hereby marked "advertisement" in accordance with 18 USC section 1734 solely to indicate this fact. The opinions expressed in this publication are those of the authors and are not attributable to the sponsors or the publisher, Editor, or Editorial Board of The Journal of Nutrition.

↵2 This work was supported by the Functional Foods Task Force of the European branch of the International Life Sciences Institute (ILSI Europe). Industry members of this task force (2007–2010) are Abbott Nutrition, Ajinomoto Europe, Barilla G. & R. Fratelli, Bayer Crop Science Bio Science, Beverage Partners Worldwide, Bionov, Cadbury, Cargill, Coca-Cola Europe, Colloïdes Naturels International, CSM, Danisco, Danone, Dow Europe, DSM, Friesland Campina, Frutarom, International Nutrition Company (INC), Kellogg Europe, Kraft Foods, La Morella Nuts, Mars, Martek Biosciences Corporation, Mc Neil Nutritionals, Monsanto Europe, Naturex, Nestlé, Pepsi Co International, Pfizer Consumer Health Care, Procter & Gamble, Puleva, Raisio Group, Red Bull, Raffinerie Tirlemontoise – ORAFTI, Soremartec Italia – Ferrero Group, Südzucker/BENEO Group, Syral, Tate & Lyle Ingredients, Ülker Bisküvi, Unilever, Valio, Rudolf Wild, Wimm-Bill-Dann Foods, Wrigley, and Yakult Europe. The opinions expressed herein are those of the authors and do not necessarily represent the views of ILSI Europe nor those of its member companies.

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The biological relevance of direct antioxidant effects of polyphenols for cardiovascular health in humans is not established
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