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Preventing cardiovascular disease in children and adolescents with type 2 diabetes mellitus
N Rampersaud - 2012 - Abstract: Problem: In the United States, there is an increasing incidence of diabetes mellitus type 2 (DMT2) in adolescents and children. Cardiovascular disease is a significant and common complication of DMT2. Therefore, it is imperative to identify cardiovascular risk ...
Problem: In the United States, there is an increasing incidence of diabetes mellitus type 2 (DMT2) in adolescents and children. Cardiovascular disease is a significant and common complication of DMT2. Therefore, it is imperative to identify cardiovascular risk factors and implement the appropriate intervention in this specific population with DMT2. The goal of this study is to determine the most effective method to screen for cardiovascular disease and identify an appropriate intervention in adolescents and children with DMT2 to slow or ideally halt the progression of cardiovascular disease.
Conclusions: From the articles reviewed in this study, it can be concluded that weight loss as achieved by exercise results in improved glycemic control, improved dyslipidemia, reduced BM1 and reduced waist circumference in adolescents with DMT1, and after one year of bariatric surgery (Roux en Y gastric bypass) there was evidence of remission of DMT2 in the majority of adolescent patients. Therefore, research is proposed to evaluate a comparison of whether weight loss or medical management is more effective in reducing cardiovascular disease as tested by utilizing an ultrasound to measure the carotid intima thickness in adolescents with DMT2 as a marker of atherosclerosis, providing a predictive marker of future cardiovascular disease.
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Preventing cardiovascular disease in children and adolescents with type 2 diabetes mellitus |
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