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Genetic issues in pediatric cardiomyopathy: Future research directions
W Chung... - Progress in Pediatric Cardiology, 2011 - Elsevier Pediatric cardiomyopathies are extremely heterogeneous in etiology and are thus associated
with variability in prognosis and response to therapy. With increasing availability of clinical diagnostic
tools and research methods to molecularly characterize genetic forms of cardiomyopathy ...
Pediatric cardiomyopathies are extremely heterogeneous in etiology and are thus associated with variability in prognosis and response to therapy. With increasing availability of clinical diagnostic tools and research methods to molecularly characterize genetic forms of cardiomyopathy and identify viral pathogens in myocarditis, we have the opportunity to define pediatric cardiomyopathies by molecular subtype and characterize the natural history of each subtype. By understanding the natural histories of the subtypes of pediatric cardiomyopathies, we can develop biomarkers for early stages of diseases and disease progression, and lay the foundations necessary for future clinical trials for treatment and primary prevention.
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Genetic issues in pediatric cardiomyopathy: Future research directions |
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