Heart Care Info - Heart Disease Prevention & Treatment

Effectiveness of Cardiac Resynchronization Therapy in Diabetic Patients with Ischemic and Nonischemic Cardiomyopathy

J George, A Barsheshet, AJ Moss... - Annals of ..., 2012 - Wiley Online Library Background: Diabetes mellitus (DM) increases the risk for the development of both ischemic and nonischemic cardiomyopathy. We aimed to identify differences in response to cardiac resynchronization therapy with a defibrillator (CRT-D) among DM patients with ischemic or ... [HTML]

Methods: Cox proportional hazards regression modeling was used to assess clinical response to CRT D (defined as CRT D vs. defibrillator only reduction in the risk of heart failure [HF] or death) and echocardiographic response (defined as percent reduction in left ventricular end diastolic and systolic volume [LVEDV and LVESV, respectively] at 12 month of follow up compared with baseline values) among 552 diabetic patients with ischemic (n = 367) or nonischemic (n = 185) cardiomyopathy enrolled in MADIT CRT.