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The relationship of insulin resistance and extracoronary calcification in the multi ethnic study of atherosclerosis, atherosclerosis

The relationship of insulin resistance and extracoronary calcification in the multi-ethnic study of atherosclerosis


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GH Tison, MJ Blaha, MJ Budoff, R Katz, JJ Rivera... - Atherosclerosis, 2011 - Elsevier OBJECTIVE: We hypothesized that insulin resistance, measured by the homeostasis model assessment of insulin resistance (HOMA), is independently associated with prevalent and incident extra-coronary calcification (ECC). METHODS: We studied calcium scores of the ...

We studied calcium scores of the aortic valve calcification (AVC), mitral valve calcification (MVC), thoracic aorta calcification (TAC) and aortic valve root calcification (AVR) in 6104 MESA participants not on diabetes medication who had baseline cardiac CT scans; 5312 had follow-up scans (mean 2.4 years). Relative-risk regression modeled prevalent and incident ECC adjusted for baseline demographics (model 1), and additionally for CVD risk factors (model 2).

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The relationship of insulin resistance and extracoronary calcification in the multi-ethnic study of atherosclerosis
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