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Polymorphisms of< i> LTA</i>,< i> LGALS2</i>, and< i> PSMA6</i> genes and coronary atherosclerosis: A pathological study of 1503 consecutive autopsy cases
S Ikeda, N Tanaka, T Arai, K Chida, M Muramatsu... - Atherosclerosis, 2012 - Elsevier Objective Recent genome-wide association studies have identified polymorphisms of lymphotoxin-α (LTA), galectin-2 (LGALS2), and proteasome subunit a type 6 (PSMA6) genes as genetic risk factors for myocardial infarction (MI). However, their effects on coronary ...
► The subjects of our study are Japanese consecutive autopsy cases. ► These subjects have abundant information of the pathological and clinical. ► Coronary atherosclerosis is the most important intermediate phenotype of MI. ► The prevalence of pathological and clinical MI increased with the severity of CSI. ► The polymorphisms of LTA and LGALS2 were associated with CSI, but not with pathological MI.
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Polymorphisms of< i> LTA</i>,< i> LGALS2</i>, and< i> PSMA6</i> genes and coronary atherosclerosis: A pathological study of 1503 consecutive autopsy cases |
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