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Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE 3Leiden CETP transgenic mice with or without treatment with atorvastatin, atherosclerosis

Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE* 3Leiden. CETP transgenic mice with or without treatment with atorvastatin


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S Khnast, JWA van der Hoorn... - Journal of ..., 2012 - Objective: Aliskiren is the first commercially available, orally active, direct renin inhibitor approved to treat hypertension. The reninangiotensin system has been shown to be a significant contributor to the development of hypercholesterolemia-induced ...

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Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE* 3Leiden. CETP transgenic mice with or without treatment with atorvastatin
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