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Molecular Imaging of Macrophages in Atherosclerosis

E Aikawa, SEP New, T Miyazaki, D Fukuda... - Current Cardiovascular ..., 2012 - Springer Abstract Macrophages contribute to the initiation, progression, and acute complications of atherosclerosis. Imaging of macrophages during disease progression provides new insights into the mechanisms of atherosclerosis. Advanced imaging techniques may serve as ... [HTML]

Corosolic Acid Ameliorates Atherosclerosis in Apolipoprotein E-Deficient Mice by Regulating the Nuclear Factor-κB Signaling Pathway and Inhibiting Monocyte ...

H Chen, J Yang, Q Zhang, LH Chen... - ... journal: official journal ..., 2012 - Background: Corosolic acid (CRA) is a pentacyclic triterpene acid that has been shown to exhibit an anti-atherosclerotic effect when added to diets of low-density lipoprotein-deficient mice, but the mechanisms are unclear. The purpose of the present study was to ...

Regulatory T-Cell Response to Apolipoprotein B100–Derived Peptides Reduces the Development and Progression of Atherosclerosis in Mice

O Herbin, H Ait-Oufella, W Yu... - ... and Vascular Biology, 2012 - Am Heart Assoc ObjectiveThe immunoinflammatory response plays a critical role in the development and progression of atherosclerosis. Recent studies suggested an important role for regulatory T (Treg) cells in the inhibition of disease-related vascular inflammation. We hypothesized ...

White blood cell count is associated with carotid and femoral atherosclerosis

E Ortega, R Gilabert, I Nuez, M Cofn... - Atherosclerosis, 2012 - Elsevier OBJECTIVE: Chronic low-grade inflammation is associated with atherosclerosis. Ultrasound imaging allows measurement of intima-media thickness (IMT) and plaque. We investigated the association between inflammatory markers and carotid and femoral atherosclerosis. ... [CITATION] Erratum to Predictive value of white blood cell subtypes for long-term outcome following myocardial infarctions[Atherosclerosis 196 (2008) 405412]R Dragu, S Khoury, R Zuckerman, M Suleiman... - Atherosclerosis, 2012 - Elsevier

Polymorphisms of< i> LTA</i>,< i> LGALS2</i>, and< i> PSMA6</i> genes and coronary atherosclerosis: A pathological study of 1503 consecutive autopsy cases

S Ikeda, N Tanaka, T Arai, K Chida, M Muramatsu... - Atherosclerosis, 2012 - Elsevier Objective Recent genome-wide association studies have identified polymorphisms of lymphotoxin-α (LTA), galectin-2 (LGALS2), and proteasome subunit a type 6 (PSMA6) genes as genetic risk factors for myocardial infarction (MI). However, their effects on coronary ...

A role for CMV-specific CD4+ CX3CR1+ T cells and CMV-induced T cell immunopathology in HIV-associated atherosclerosis

K Sacre, PW Hunt, PY Hsue, E Maidji, JN Martin... - AIDS, 2012 - Objective: Human Immunodeficiency Virus (HIV)-infected subjects are at increased risk for myocardial infarction. Given observations that CMV infection, CMV-specific T cells and CX3CR1 have each been associated with atherosclerosis, we hypothesized that CMV- ...
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