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Targeting Therapeutics to the Vascular Wall in Atherosclerosis-Carrier Size Matters

P Charoenphol, S Mocherla, D Bouis, K Namdee... - Atherosclerosis, 2011 - Elsevier Vascular-targeted imaging and drug delivery systems are promising for the treatment of atherosclerosis due to the vast involvement of endothelium in the initiation and growth of plaque. Herein, we investigated the role of particle size in dictating the ability of vascular-targeted spherical ...

Cardiovascular Surgery

T Implantation - Circulation, 2011 - Am Heart Assoc BackgroundAppropriate surgical management of type A dissection is a critical factor for achieving satisfactory outcome, but the choice of optimal procedure is controversial. We retrospectively reviewed our experience with aortic arch replacement for type A dissection involving the ...

Clinical course and analysis of ten fatal cases of clozapine-induced myocarditis and comparison with 66 surviving cases

KJ Ronaldson, PB Fitzgerald, AJ Taylor... - Schizophrenia ..., 2011 - Elsevier BACKGROUND: Fatal clozapine-induced myocarditis has not been investigated systematically. We describe the clinical course of 10 fatal cases of myocarditis with clozapine and identify factors associated with fatality. METHODS: Cases of myocarditis ...

Surgery and cardiovascular outcomes: an untapped public health benefit that potentially saves lives

BM Biccard - Anaesthesia, 2012 - Wiley Online Library... the access to appropriate health interventions [23]. Ineligibility for surgery could theoretically result in the initiation of two pathways associated with inequality in cardiovascular health. Patients ineligible for surgery may have ... [HTML]

Effects of awareness and nociception on heart rate variability during general anaesthesia

R Huhle, M Burghardt, S Zaunseder... - Physiological ..., 2012 - During anaesthesia awareness and nociception are serious complications that may further lead to haemodynamic instability. Specific monitoring of depth of hypnosis and depth of analgesia based on heart rate variability (HRV) analysis is eligible to improve patient ... [HTML]
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