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Congenital heart surgery in infants: Effects of acute kidney injury on outcomes

JJ Blinder, SL Goldstein, VV Lee, A Baycroft... - The Journal of Thoracic ..., 2011 - Elsevier Objectives We sought to characterize factors and outcomes associated with postoperative acute kidney injury in infants undergoing cardiac surgery. Methods We retrospectively studied 430 infants (< 90 days) who underwent heart surgery for congenital defects. With a ...

Explanatory Models of Heart Failure Etiology

AP Clark, GJ Mc Dougall Jr... - ... of Critical Care ..., 2012 - Abstract Chronic health failure is a leading cause of hospital readmissions and is reaching epidemic proportions in the United States. Explanatory models of illness can provide insight about how people with heart failure perceive their etiology of heart failure. Six themes ...

Targeting cardiovascular disease with novel SIRT1 pathways

ZZ Chong, S Wang, YC Shang... - Future Cardiology, 2012 - Future Medicine Sirtuin (the mammalian homolog of silent information regulation 2 of yeast Saccharomyces cerevisiae) 1 (SIRT1), a NAD-dependent histone deacetylase, has emerged as a critical regulator in response to oxidative stress. Through antagonism of oxidative stress-induced ...

Frequency of heparin/platelet factor 4-dependent platelet antibodies in patients undergoing angioplasty and stenting for cardiovascular disease and their role for on- ...

T Gremmel, K Frhwirth, CW Kopp, A Kaider... - Clinical Research in ..., 2012 - Springer Abstract Background The frequency of heparin-induced platelet antibodies (H/PF4 antibodies) following heparin exposure during percutaneous intervention with stent implantation is unknown. These antibodies may activate platelets and therefore contribute ...

Expect the Unexpected: Sudden Cardiac Death in Dialysis Patients

RS Parekh - Clinical Journal of the American Society of ..., 2012 - Am Soc Nephrol Over the past decade, a number of clinical trials addressing dialysis dose and frequency and cardiovascular risk have revealed that sudden unexpected deaths are a common occurrence among incident and prevalent dialysis patients (1, 2). This high rate of out of ...
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