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Molecular Characterization of a Streptococcus gallolyticus Genomic Island Encoding a Pilus Involved in Endocarditis

C Danne, JM Entenza, A Mallet... - Journal of Infectious ..., 2011 - Background. Streptococcus gallolyticus is a causative agent of infective endocarditis associated with colon cancer. Genome sequence of strain UCN34 revealed the existence of 3 pilus loci (pil1, pil2, and pil3). Pili are long filamentous structures playing a key role as ...

Heart rate recovery after treadmill exercise testing is an independent predictor of stroke incidence in men with metabolic syndrome

J Kim, W Byun, X Sui, D Lee, YJ Cheng... - Obesity Research ..., 2011 - Elsevier BACKGROUND AND AIMS: Heart rate recovery (HRR), a measure of the heart rate which decreases after a graded exercise test, has been associated with mortality and cardiovascular diseases. However, the association between HRR and risk of stroke has ...

Histamine H (1) receptor signaling regulates effector T cell responses and susceptibility to coxsackievirus B3-induced myocarditis.

LK Case, M Moussawi, B Roberts... - Cellular ..., 2011 - Susceptibility to autoimmune myocarditis has been associated with histamine release by mast cells during the innate immune response to coxsackievirus B3 (CVB3) infection. To investigate the contribution of histamine H (1) receptor (H (1) R) signaling to CVB3- ...

Historical Reflections on the Inflammatory Aspects of Atherosclerosis

FJ Nieto - Inflammation and Atherosclerosis, 2012 - Springer A sudden shift in the understanding of the importance of inflammation in the pathophysiology of atherosclerosis occurred around the turn of the millennium. During most of the twentieth century, atherosclerosis was considered a degenerative disease, mostly ...

Combination of Two Urinary Biomarkers Predicts Acute Kidney Injury After Adult Cardiac Surgery

D Katagiri, K Doi, K Honda... - The Annals of ..., 2012 - Soc Thorac Surgeons Background: Urinary L-type fatty acid-binding protein (L-FABP) has not been evaluated for adult post-cardiac surgery acute kidney injury (AKI) to date. This study was undertaken to evaluate a biomarker panel consisting of urinary L-FABP and N-acetyl-β-D- ...
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