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Gadolinium Chelate Kinetics in Cardiac MR Imaging of Myocarditis: Comparison to Acute Myocardial Infarction and Impact on Late Gadolinium Enhancement

A Jacquier, C Prost, N Amabile, R Giorgi... - Investigative ..., 2011 - Methods: Seventeen patients with acute myocarditis and 12 with acute myocardial infarction underwent Look-Locker sequences before and after administration of 0.2 mmol/kg gadolinium chelate for a period of 14 minutes. The apparent longitudinal relaxation rates (R'1) were ...

Can Brain Natriuretic Peptide Be Used to Guide the Management of Patients With Heart Failure and a Preserved Ejection Fraction?

M Packer - Circulation: Heart Failure, 2011 - Am Heart Assoc Physicians make the diagnosis of heart failure when patients present with exercise intolerance that is limited by dyspnea, fatigue, or both and that can be attributed to an identifiable abnormality of cardiac function. Patients with exertional symptoms attributable to severe primary ...

Redox modification of cell signaling in the cardiovascular system

D Shao, S Oka, CD Brady, J Haendeler... - Journal of Molecular and ..., 2011 - Elsevier Oxidative stress is presumed to be involved in the pathogenesis of many diseases, including cardiovascular disease. However, oxidants are also generated in healthy cells, and increasing evidence suggests that they can work as signaling molecules. Intracellular reduction- ... [BOOK]

Diabetes and Coronary Heart Disease

GT Mc Mahon - Coronary Heart Disease, 2012 - Springer Cardiovascular disease is the leading cause of death among patients with diabetes. Hyperglycemia, hypertension, and dyslipidemia associated with type 2 diabetes each contribute to the accelerated atherosclerosis that occurs in this disease. An integrated ...

Circulating microRNAs to identify human heart failure

AG Seto... - European Journal of Heart Failure, 2012 - Micro RNAs (mi RNAs) are short, non-coding RNAs that act in a proteinnucleic acid complex, called the RNA-induced silencing complex (RISC), to repress gene expressioneither through destabilization of an m RNA, or through inhibition of protein translation. The ...
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