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A pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease

TA Addona, X Shi, H Keshishian, DR Mani... - Nature ..., 2011 - We developed a pipeline to integrate the proteomic technologies used from the discovery to the verification stages of plasma biomarker identification and applied it to identify early biomarkers of cardiac injury from the blood of patients undergoing a therapeutic, planned myocardial ...

... Free Testosterone Concentration in Older Women Is Associated with Greater Bone Mineral Density, Lean Body Mass, and Total Fat Mass: The Cardiovascular Health ...

CM Rariy, SJ Ratcliffe, R Weinstein... - Journal of Clinical ..., 2011 - Endocrine Soc Address all correspondence and requests for reprints to: Anne R. Cappola, MD, Sc.M., Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, 764 CRB, 415 Curie Boulevard, Philadelphia, Pennsylvania 19104. E-mail: acappola{at} ...

Global DNA Methylation and Risk of Subclinical Atherosclerosis in Young Adults: The Pathological Determinants of Atherosclerosis in Youth (PDAY) Study

J Bressler, LC Shimmin, E Boerwinkle... - Atherosclerosis, 2011 - Elsevier Objective The association between hepatic global DNA methylation measured using pyrosequencing technology and the risk of subclinical atherosclerosis was examined in the Pathological Determinants of Atherosclerosis in Youth (PDAY) study. PDAY is a bi-racial ...

Extracranial-Intracranial Bypass Surgery for Stroke Prevention in Hemodynamic Cerebral Ischemia

WJ Powers, WR Clarke, RL Grubb Jr... - JAMA: The Journal of ..., 2011 - Am Med Assoc Abstract Context Patients with symptomatic atherosclerotic internal carotid artery occlusion (AICAO) and hemodynamic cerebral ischemia are at high risk for subsequent stroke when treated medically. Objective To test the hypothesis that extracranial-intracranial (EC-IC) ...

Cardiovascular Risk Factors and 10-Year Risk for Coronary Heart Disease Among Korean Women

S Boo - 2012 - Background. More women than men die of cardiovascular disease (CVD) in Korea. Of important concern to Korean women is the dramatically increasing mortality rate from coronary heart disease (CHD). Despite the significant burden of CHD in Korean women ...
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