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Knockout of the Na, K-ATPase α2-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension

TN Rindler, I Dostanic, VM Lasko... - American Journal of ..., 2011 - Am Physiological Soc Abstract The α 2-isoform of Na, K-ATPase (α 2) is thought to play a role in blood pressure regulation, but the specific cell type (s) involved have not been identified. Therefore, it is important to study the role of the α 2 in individual cell types in the cardiovascular system. ...

Effects of Aggressive Versus Moderate Glycemic Control on Clinical Outcomes in Diabetic Coronary Artery Bypass Graft Patients

HL Lazar, MM Mc Donnell, S Chipkin... - Annals of ..., 2011 - Abstract Objective: This study sought to determine whether aggressive glycemic control (90120 mg/d L) would result in more optimal clinical outcomes and less morbidity than moderate glycemic control (120180 mg/d L) in diabetic patients undergoing coronary artery bypass ...

Advances in noninvasive imaging for evaluating clinical risk and guiding therapy in carotid atherosclerosis

AJ Degnan, VEL Young... - Expert Review of ..., 2012 - Managing asymptomatic carotid atherosclerosis with a view to preventing ischemic stroke is a challenging task. As the annual risk of stroke in untreated asymptomatic patients on average is less than the risk of surgical intervention, the key question is how to identify ...

Nerve Growth Factor Gene Therapy Using Adeno-Associated Viral Vectors Prevents Cardiomyopathy in Type 1 Diabetic Mice

M Meloni, B Descamps, A Caporali, L Zentilin... - Diabetes, 2012 - Am Diabetes Assoc Abstract Diabetes is a cause of cardiac dysfunction, reduced myocardial perfusion, and ultimately heart failure. Nerve growth factor (NGF) exerts protective effects on the cardiovascular system. This study investigated whether NGF gene transfer can prevent ...

Randomized, Controlled Study of Telcagepant in Patients With Migraine and Coronary Artery Disease

TW Ho, AP Ho, BR Chaitman... - ... : The Journal of ..., 2012 - Wiley Online Library Objective.To evaluate the efficacy of telcagepant in patients with migraine and coronary artery disease. Background.Calcitonin gene-related peptide receptor antagonists, such as telcagepant, may be useful for acute migraine treatment in patients with cardiovascular ... [CITATION] Should we screen for coronary artery disease in asymptomatic chronic dialysis patients?AS De Vriese, SJ Vandecasteele, B Van den Bergh... - Kidney International, 2012 [PDF]
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