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The progression of hypertensive heart disease

MH Drazner - Circulation, 2011 - Am Heart Assoc Hypertension remains a major public health problem associated with considerable morbidity and mortality. Hypertensive heart disease is a constellation of abnormalities that includes left ventricular hypertrophy (LVH), systolic and diastolic dysfunction, and their clinical ...

Urinary Sodium Excretion and Cardiovascular Disease Mortality

CM Rebholz... - JAMA: The Journal of the American Medical ..., 2011 - Am Med Assoc A major source of bias in this study was misclassification of urinary sodium excretion. A single 24-hour urine sample, which was used for all the analyses, cannot represent usual sodium intake at the individual level. Nor can it be used to accurately classify individuals into categories ...

Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft Surgery in Left Main Coronary Artery Disease: A Meta-Analysis of Randomized Clinical ...

D Capodanno, GW Stone... - Journal of the ..., 2011 - Am Coll Cardio Found... CI = confidence interval; LEMANS = Left Main Coronary Artery Stenting; MACCE = major adverse cardiac and cerebrovascular event(s); MI = myocardial infarction; PRECOMBAT = Premier of Randomized Comparison of Bypass Surgery Versus Angioplasty Using Sirolimus ...

Historical Reflections on the Inflammatory Aspects of Atherosclerosis

FJ Nieto - Inflammation and Atherosclerosis, 2012 - Springer A sudden shift in the understanding of the importance of inflammation in the pathophysiology of atherosclerosis occurred around the turn of the millennium. During most of the twentieth century, atherosclerosis was considered a degenerative disease, mostly ...

... outcomes in patients with heart failure, left ventricular dysfunction, and dyssynchrony: insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial

N Lopez-Andrs, P Rossignol... - ... of heart failure, 2012 - Aims Circulating biomarkers of collagen turnover reflect extracellular cardiac matrix (ECCM) remodelling. The extent to which the success of cardiac resynchronization therapy (CRT) is influenced by the degree of cardiac fibrosis and whether CRT can influence matrix ...
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