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Metabolic syndrome, obstructive sleep apnea, and risk of cardiovascular disease

JM Parish - Sleep and Breathing, 2011 - Springer This editorial published in the same issue as the paper by Roche et al., Obstructive sleep apnea and the metabolic syndrome in an elderly healthy population: the SYNAPSE cohort is relevant to the knowledge about the adverse health consequences of obstructive sleep apnea and ...

Association of cardiomegaly with coronary artery histopathology and its relationship to atheroma.

RE Tracy - Journal of atherosclerosis and thrombosis, 2011 - AIMS: Hypertrophied hearts at autopsy often display excessive coronary artery atherosclerosis, but the histopathology of coronary arteries in hearts with and without cardiomegaly has rarely been compared. METHODS: In this study, forensic autopsies ...

Guidelines for the diagnosis and antibiotic treatment of endocarditis in adults: a report of the Working Party of the British Society for Antimicrobial Chemotherapy

FK Gould, DW Denning, TSJ Elliott... - Journal of ..., 2011 - Br Soc Antimicrob Chemo Abstract The BSAC guidelines on treatment of infectious endocarditis (IE) were last published in 2004. The guidelines presented here have been updated and extended to reflect developments in diagnostics, new trial data and the availability of new antibiotics. ...

Role of the arachidonate 5-lipoxygenase enzymatic pathway in coronary heart disease

AM Schentrup - 2012 - Abstract: Evidence indicates that the arachidonate 5-lipoxyagense enzymatic pathway may play a pivotal role in cardiovascular disease. During this investigation, we achieved three aims. We developed a convenient and accurate pyrosequencing protocol for genotyping a ...

Inherent and Benzo [a] pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Lifespan, Atherosclerosis, Cardiac Gene Expression, and ...

JS Kerley-Hamilton, HW Trask, CJA Ridley... - Toxicological ..., 2012 - Soc Toxicology Abstract Little is known of the environmental factors that initiate and promote disease. The aryl hydrocarbon receptor (AHR) is a key regulator of xenobiotic metabolism and plays a major role in gene/environment interactions. The AHR has also been demonstrated to ...
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