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Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis

L Hong, ZZ Xie, YH Du, YB Tang, J Tao, XF Lv... - Atherosclerosis, 2011 - Elsevier Methods and ResultsTreatment of RAW264.7 cells with ox-LDL increased intracellular cholesterol content as well as cell volume. After ox-LDL treatment, the resting [Cl - ] i in isotonic solution was decreased. Hypotonic solution reduced [Cl - ] i and evoked volume-regulated Cl - current ...

Regionalization in Neonatal Congenital Heart Surgery: The Impact of Distance on Outcome After Discharge

NM Pinto, J Lasa, TE Dominguez, G Wernovsky... - Pediatric ..., 2011 - Springer Abstract Studies have shown improved perioperative outcomes after neonatal heart surgery at centers with greater surgical volumes. The impact of increasing distance from such centers on outcome after discharge has not yet been reported. Chart review and cross- ...

Relation of red cell distribution width with the presence, severity, and complexity of coronary artery disease

T Isik, H Uyarel, IH Tanboga, M Kurt... - Coronary Artery ..., 2011 - Objectives: Red cell distribution width (RDW) is a measure of the heterogeneity of cell size in the peripheral blood and has been shown to be an independent correlate of adverse outcomes in healthy participants and in some cardiac conditions. We examined the ...

Heart failure and socioeconomic status: accumulating evidence of inequality

NM Hawkins, PS Jhund... - ... of Heart Failure, 2012 - Aims Socioeconomic status (SES) is a powerful predictor of incident coronary disease and adverse cardiovascular outcomes. Understanding the impact of SES on heart failure (HF) development and subsequent outcomes may help to develop effective and equitable ...

Effects of Variation in Temperature Management on Cerebral Performance Category Scores in Patients Who Received Therapeutic Hypothermia Post Cardiac Arrest.

S Sendelbach, MO Hearst, PJ Johnson... - ..., 2012 - AIM: To assess differences in Cerebral Performance Category (CPC) in patients who received therapeutic hypothermia post cardiac arrest by time to initiation, time to target temperature, and duration of Therapeutic Hypothermia (TH). METHODS: A secondary ...
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