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Genetical genomics of Th1 and Th2 immune response in a baboon model of atherosclerosis risk factors

A Vinson, JE Curran, MP Johnson, TD Dyer... - Atherosclerosis, 2011 - Elsevier We employed a maximum likelihood-based variance decomposition approach to estimate additive genetic effects on transcript levels generated from a gene expression profile of lymphocytes in 499 pedigreed baboons maintained on a basal diet. Transcript levels for 57 genes ...

Use of antidepressants for 12 weeks or longer is associated with a reduced incidence of heart attack in depressed adults.

RC Ziegelstein - Evidence-based mental health, 2011 - ncbi.nlm.nih.gov1. Evid Based Ment Health. 2011 Aug;14(3):67. Use of antidepressants for 12 weeks or longer is associated with a reduced incidence of heart attack in depressed adults. Ziegelstein RC. Johns Hopkins Bayview Medical Center ... [CITATION] Better Hospital Care for Aboriginal and Torres Strait Islander People Experiencing Heart Attack V Wade - Heart, Lung and Circulation, 2011 - Elsevier BV [BOOK]

Congenital heart surgery in infants: Effects of acute kidney injury on outcomes

JJ Blinder, SL Goldstein, VV Lee, A Baycroft... - The Journal of Thoracic ..., 2011 - Elsevier Objectives We sought to characterize factors and outcomes associated with postoperative acute kidney injury in infants undergoing cardiac surgery. Methods We retrospectively studied 430 infants (< 90 days) who underwent heart surgery for congenital defects. With a ...

Carotid Atherosclerosis Predicts Lower Cognitive Test Results: A 7-Year Follow-Up Study of 4,371 Stroke-Free Subjects–The Tromsø Study

KA Arntzen, H Schirmer, SH Johnsen... - Cerebrovascular ..., 2012 - ; i> Background:</i> Carotid artery atherosclerosis is a major risk factor for stroke and subsequent cognitive impairment. Prospective population studies have shown associations between carotid intima-media thickness (IMT) and stenosis and cognitive decline and ...

Myocardial transcriptome analysis of human arrhythmogenic right ventricular cardiomyopathy

A Gaertner, P Schwientek... - Physiological ..., 2012 - Am Physiological Soc Abstract Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiomyopathy primarily of the right ventricle characterized through fibrofatty replacement of cardiomyocytes. The genetic etiology in ARVC patients is most commonly caused by ...
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