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Effect of Defibrillation Energy Dose During In-Hospital Pediatric Cardiac Arrest

PA Meaney, VM Nadkarni, DL Atkins, MD Berg... - Pediatrics, 2011 - Am Acad Pediatrics RESULTS Of 266 children with 285 events, 173 of 285 (61%) survived the event and 61 of 266 (23%) survived to discharge. Termination of fibrillation after initial shock was achieved for 152 of 285 (53%) events. Termination of fibrillation with 2 10 J/kg was much less frequent ...

RAS signaling pathway mutations and hypertrophic cardiomyopathy: getting into and out of the thick of it

BD Gelb, M Tartaglia, C Boshoff... - The Journal of ..., 2011 - Am Soc Clin Investig In this issue of the JCI, Wu et al. and Marin et al. describe two new mouse models of inherited disorders of the RAS/MAPK signal transduction pathway that display hypertrophic cardiomyopathy (HCM); the model from the former paper was from a gain-of-function Raf1 mutation, and ...

Influence of Erythrocyte Transfusion on the Risk of Acute Kidney Injury after Cardiac Surgery Differs in Anemic and Nonanemic Patients

K Karkouti, DN Wijeysundera, TM Yau... - ..., 2011 - * Associate Professor, Department of Anesthesia, Toronto General Hospital, University Health Network, Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada. Assistant Professor, Department of Anesthesia, Toronto ...

A Genetic Risk Score is Associated with Incident Cardiovascular Disease and Coronary Artery Calcium-The Framingham Heart Study

G Thanassoulis, GM Peloso, MJ Pencina... - Circulation: ..., 2012 - Am Heart Assoc... The addition of recently discovered SNPs did not significantly improve the performance of this GRS. Key words: Genetics, single nucleotide polymorphisms, cardiovascular disease, coronary heart disease, risk prediction, reclassification ...

Coronary Artery Disease Is Associated with Cognitive Decline Independent of Changes on Magnetic Resonance Imaging in Cognitively Normal Elderly Adults

L Zheng, WJ Mack, HC Chui, L Heflin... - Journal of the ..., 2012 - Wiley Online Library Objectives To examine in cognitively normal elderly adults whether vascular factors predict cognitive decline and whether these associations are mediated by magnetic resonance imaging (MRI) measures of subclinical vascular brain injury. Design
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