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Inflammatory Markers and Neuropsychological Functioning: The Framingham Heart Study

AL Jefferson, JM Massaro, AS Beiser... - ..., 2011 - Background/Aims: We hypothesized that inflammatory markers are cross-sectionally and longitudinally associated with neuropsychological indicators of early ischemia and Alzheimer's disease. Methods: Framingham Offspring Study participants, free of clinical stroke or dementia (n = ...

08 Increased risk of cardiac arrhythmia in rats exposed to diesel exhaust air pollution is mediated by the nociceptive transient receptor potential A1 (TRPA1)

MS Hazari, C Lamb, AP Carll, Q Krantz... - Heart, 2011 - The electro-mechanical window (EMw) is a recently proposed biomarker describing the temporal difference between electrical and mechanical events in beating hearts and is a precursor to identify Torsade de Pointes (Td P) risk in the anaesthetised dog.1 In follow-up studies, conscious ... [PDF]

Developmentally Regulated SCN5A Splice Variant Potentiates Dysfunction of a Novel Mutation Associated with Severe Fetal Arrhythmia

LL Murphy, AJ Moon-Grady, BF Cuneo, RT Wakai... - Heart Rhythm, 2011 - Elsevier Background Congenital long-QT syndrome (LQTS) may present during fetal development and can be life-threatening. The molecular mechanism for the unusual early onset of LQTS during fetal development is unknown. Objective We sought to elucidate the molecular ...

Pulmonary Pressures and Death in Heart Failure: A Community Study

F Bursi, SM Mc Nallan, MM Redfield... - Journal of the ..., 2012 - Am Coll Cardio Found Objectives: The purpose of this study was to determine among community patients with heart failure (HF) whether pulmonary artery systolic pressure (PASP) assessed by Doppler echocardiography was associated with death and improved risk prediction over ...

Paediatric cardiac rehabilitation in congenital heart disease: a systematic review

AU Tikkanen, AR Oyaga, OA Riao... - Cardiology in the ..., 2012 - Cambridge Univ Press Background Advances in medical and surgical care have contributed to an important increase in the survival rates of children with congenital heart disease. However, survivors often have decreased exercise capacity and health-related issues that affect their quality ...
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