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Alteration of volume-regulated chloride channel during macrophage-derived foam cell formation in atherosclerosis

L Hong, ZZ Xie, YH Du, YB Tang, J Tao, XF Lv... - Atherosclerosis, 2011 - Elsevier Methods and ResultsTreatment of RAW264.7 cells with ox-LDL increased intracellular cholesterol content as well as cell volume. After ox-LDL treatment, the resting [Cl - ] i in isotonic solution was decreased. Hypotonic solution reduced [Cl - ] i and evoked volume-regulated Cl - current ...

IL-6-mediated Th17 differentiation through RORγt is essential for the initiation of experimental autoimmune myocarditis

T Yamashita, T Iwakura... - Cardiovascular ..., 2011 - Methods and results To induce EAM, mice were immunized twice with α-myosin heavy chain peptide. Three weeks after the first injection, the cardiac expression of the Th17-specific transcription factor, retinoic acid receptor-related orphan nuclear receptor (ROR γt), was up-regulated. ...

Circulating Long-Chain ω-3 Fatty Acids and Incidence of Congestive Heart Failure in Older Adults: The Cardiovascular Health Study

D Mozaffarian, RN Lemaitre, IB King... - Annals of internal ..., 2011 - Am Coll Physicians Background: Few previous studies have evaluated associations between long-chain ω-3 fatty acids and incidence of congestive heart failure (CHF), and those that have are typically based on diet questionnaires and yield conflicting results. Circulating fatty acid concentrations ...

Left ventricle remodelling is associated with sleep‐disordered breathing in non‐ischaemic cardiopathy with systolic dysfunction

T DAMY, A PAULINO, L MARGARIT... - Journal of Sleep ..., 2011 - Wiley Online Library DAMY, T., PAULINO, A., MARGARIT, L., DROUOT, X., STOICA, M., VERMES, E., GUERET, P., ADNOT, S., DUBOIS RANDE, J.-L., D''ORTHO, M.-P. and HITTINGER, L.(2011), Left ventricle remodelling is associated with sleep-disordered breathing in non-ischaemic ...

Risk factors for onset of disability among older persons newly diagnosed with heart failure: the cardiovascular health study.

SI Chaudhry, G Mc Avay, Y Ning... - Journal of cardiac ..., 2011 - BACKGROUND: As the heart failure population continues to age, disability is becoming an increasingly important issue. Our objective was to identify risk factors for the onset of disability in activities of daily living among older persons with heart failure. METHODS: ...
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