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Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy

C Marchesi, R Essalmani, CA Lemari... - Journal of Molecular ..., 2011 - Springer Abstract Proprotein convertase (PC) 5/6 belongs to a family of secretory proteases involved in proprotein proteolysis. Several studies suggest a role for PC5/6 in cardiovascular disease. Because lethality at birth of mice lacking PC5/6 precluded elucidation of its function in the adult, we ...

Complete Heart Block Associated With Tricuspid Valve Endocarditis Due to Extended Spectrum [beta]-Lactamase-Producing Escherichia coli

CB Fordyce, RA Leather, E Partlow... - Canadian Journal of ..., 2011 - Elsevier We report a case of complete heart block associated with tricuspid endocarditis due to extended-spectrum β-lactamaseproducing Escherichia coli (ESBL E. coli) following a transrectal prostate biopsy. This is the first report of complete heart block associated with tricuspid ...

Bartonella Infective Endocarditis of a Prosthetic Aortic Valve with a Subvalvular Abscess

J Idrees, TB Albacker, SM Gordon... - Journal of Cardiac ..., 2011 - Wiley Online Library∗ Department of Thoracic and Cardiovascular Surgery, Department of Infectious Disease, Department of Cardiothoracic Anesthesia, and Department of Cardiology, Cleveland Clinic, Cleveland, Ohio ... ABSTRACT A patient with a prosthetic aortic valve, and culture ...

Cardiovascular oscillations at the bedside: early diagnosis of neonatal sepsis using heart rate characteristics monitoring

JR Moorman, JB Delos, AA Flower... - Physiological ..., 2011 - We have applied principles of statistical signal processing and nonlinear dynamics to analyze heart rate time series from premature newborn infants in order to assist in the early diagnosis of sepsis, a common and potentially deadly bacterial infection of the ...

White blood cell count is associated with carotid and femoral atherosclerosis.

E Ortega, R Gilabert, I Nuez, M Cofn... - ..., 2012 - OBJECTIVE: Chronic low-grade inflammation is associated with atherosclerosis. Ultrasound imaging allows measurement of intima-media thickness (IMT) and plaque. We investigated the association between inflammatory markers and carotid and femoral atherosclerosis. ...
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