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Depression After Heart Attack

RB Williams - Circulation, 2011 - Am Heart Assoc Depression is 3 times more common in patients after a heart attack than in the general population, with 15% to 20% of heart attack victims qualifying for a diagnosis of major depressive disorder, and a far greater proportion experiencing increased levels of depressive ...

Targeting Therapeutics to the Vascular Wall in Atherosclerosis-Carrier Size Matters

P Charoenphol, S Mocherla, D Bouis, K Namdee... - Atherosclerosis, 2011 - Elsevier Vascular-targeted imaging and drug delivery systems are promising for the treatment of atherosclerosis due to the vast involvement of endothelium in the initiation and growth of plaque. Herein, we investigated the role of particle size in dictating the ability of vascular-targeted spherical ...

Can Brain Natriuretic Peptide Be Used to Guide the Management of Patients With Heart Failure and a Preserved Ejection Fraction?

M Packer - Circulation: Heart Failure, 2011 - Am Heart Assoc Physicians make the diagnosis of heart failure when patients present with exercise intolerance that is limited by dyspnea, fatigue, or both and that can be attributed to an identifiable abnormality of cardiac function. Patients with exertional symptoms attributable to severe primary ...

Therapeutic Potential for HDAC Inhibitors in the Cardiovascular System

TA Mc Kinsey - Annual Review of Pharmacology and ..., 2012 - Abstract Reversible protein acetylation provides a central mechanism for controlling gene expression and cellular signaling events. Two pharmacological inhibitors of protein deacetylation are currently approved for the treatment of human cancer, and numerous ...

Syphilitic aortic regurgitation: A sexually transmissible cardiopathy.

M Madani, K Rissoul, MR Ajjaja... - ... de cardiologie et d' ..., 2011 - Syphilitic cardiovascular complications are currently rare. It concerns the tertiary phase of the disease and results in sacciform aneurisms of the thoracic aorta or ostial coronary artery stenosis. Syphilitic aortic regurgitation is even more rare. We illustrate it by a clinical ...
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