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Insulin Resistance and the Relationship of a Dyslipidemia to Coronary Heart Disease: The Framingham Heart Study

SJ Robins, A Lyass, JP Zachariah... - ... and Vascular Biology, 2011 - Am Heart Assoc Methods and Results Lower and higher fasting plasma HDL-C and triglyceride concentrations (defined at the study population median) and presence or absence of IR (defined by upper quartile Homeostatic Model Assessment values) were related to the development of myocardial ...

Trends in Out-of-Hospital Deaths Due to Coronary Heart Disease in Sweden (1991 to 2006) Clinical Perspective

K Dudas, G Lappas, S Stewart... - Circulation, 2011 - Am Heart Assoc Methods and Results Record linkage documented all case subjects 35 to 84 years of age in Sweden during 1991 to 2006 with a first major coronary event (out-of-hospital coronary death or hospitalization for acute myocardial infarction). Of the 384 597 cases identified, 111 ...

Lifetime Risks for Cardiovascular Disease Mortality by Cardiorespiratory Fitness Levels Measured at Ages 45, 55, and 65 Years in Men:: The Cooper Center ...

JD Berry, B Willis, S Gupta, CE Barlow... - Journal of the American ..., 2011 - Elsevier Objectives The purpose of this study was to determine the association between fitness and lifetime risk for cardiovascular disease (CVD). Background Higher levels of traditional risk factors are associated with marked differences in lifetime risks for CVD. However, data are ...

Do patients at high risk of nonsudden cardiac death benefit from prophylactic ICD therapy?

PA Scott, LD Sterns... - Current Opinion in Cardiology, 2011 - Abstract Purpose of review: Randomized controlled trials have established that prophylactic implantable cardioverter defibrillator (ICD) therapy improves survival in patients with reduced left ventricular ejection fraction (LVEF). However, mortality reduction is not ...

A Genetic Risk Score is Associated with Incident Cardiovascular Disease and Coronary Artery Calcium-The Framingham Heart Study

G Thanassoulis, GM Peloso, MJ Pencina... - Circulation: ..., 2012 - Am Heart Assoc... The addition of recently discovered SNPs did not significantly improve the performance of this GRS. Key words: Genetics, single nucleotide polymorphisms, cardiovascular disease, coronary heart disease, risk prediction, reclassification ...
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