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Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy

C Marchesi, R Essalmani, CA Lemari... - Journal of Molecular ..., 2011 - Springer Abstract Proprotein convertase (PC) 5/6 belongs to a family of secretory proteases involved in proprotein proteolysis. Several studies suggest a role for PC5/6 in cardiovascular disease. Because lethality at birth of mice lacking PC5/6 precluded elucidation of its function in the adult, we ...

The Registry of the International Society for Heart and Lung Transplantation: Fourteenth Pediatric Heart Transplantation Report—2011

R Kirk, LB Edwards, AY Kucheryavaya... - The Journal of Heart ..., 2011 - No abstract is available. To read the body of this article, please view the Full Text online. ... 2011 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved. ... Visit Sci Verse Science Direct to see if you have access via your ...

Explanatory Models of Heart Failure Etiology

AP Clark, GJ Mc Dougall Jr... - ... of Critical Care ..., 2012 - Abstract Chronic health failure is a leading cause of hospital readmissions and is reaching epidemic proportions in the United States. Explanatory models of illness can provide insight about how people with heart failure perceive their etiology of heart failure. Six themes ...

Noninvasive Imaging for Coronary Artery Disease

R Nezafat, SN Hong, P Hu, MH Moghari... - Magnetic Resonance ..., 2012 - Springer Coronary artery disease (CAD) is the largest killer of Americans. Approximately every 25 s, an American will have a coronary event, and approximately every minute, someone will die of one [1]. In 2010, an estimated 785,000 Americans will have a myocardial infarction, and ...

Effects of Pycnogenol on endothelial function in patients with stable coronary artery disease: a double-blind, randomized, placebo-controlled, cross-over study

F Enseleit, I Sudano, D Priat... - European Heart ..., 2012 - Eur Soc Cardiology Aims Extracts from pine tree bark containing a variety of flavonoids have been used in traditional medicine. Pycnogenol is a proprietary bark extract of the French maritime pine tree (Pinus pinaster ssp. atlantica) that exerts antioxidative, anti-inflammatory, and anti- ...
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