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... -Transcriptional Silencing of SCN1B and SCN2B Genes Modulates Late Sodium Current in Cardiac Myocytes from Normal Dogs and Dogs with Chronic Heart Failure

S Mishra, NA Undrovinas... - American Journal of ..., 2011 - Am Physiological Soc The emerging paradigm for Na + current in heart failure (HF) is that its transient component (I Na T ) responsible for the action potential (AP) upstroke is decreased, whereas the late component (I Na L ) involved in AP plateau is augmented. Here we tested whether Na v β 1 and Na v ...

Carotid Arterial Wall Characteristics Are Associated With Incident Ischemic Stroke But Not Coronary Heart Disease in the Atherosclerosis Risk in Communities (ARIC) ...

EY Yang, L Chambless, AR Sharrett, SS Virani... - Stroke, 2011 - Am Heart Assoc Abstract Background and PurposeUltrasound measurements of arterial stiffness are associated with atherosclerosis risk factors, but limited data exist on their association with incident cardiovascular events. We evaluated the association of carotid ultrasound- ...

Effect of Correcting for Long-Term Variation in Major Coronary Heart Disease Risk Factors: Relative Hazard Estimation and Risk Prediction in the Atherosclerosis Risk ...

NP Paynter, CM Crainiceanu, AR Sharrett... - Annals of ..., 2012 - Elsevier Purpose To examine the effect of correcting coronary heart disease (CHD) risk factors for long-term within-person variation on CHD risk. Methods By using 5533 men and 7301 women from the Atherosclerosis Risk in Communities (ARIC) study, we compared models ...

Using maximum heart rate as a rapid screening tool to determine optimum temperature for aerobic scope in Pacific salmon Oncorhynchus spp.

MT Casselman, K Anttila... - Journal of Fish Biology, 2012 - Wiley Online Library The meanse optimum temperature (T opt) for aerobic scope in juvenile coho salmon Oncorhynchus kisutch was determined to be 17 00 7 C. The repeated measures protocol took 3 weeks to complete the T opt determination using 12 fish tested at five temperatures ...

Prevalence of Cardiomyopathy in Italian Asymptomatic Children With Electrocardiographic T-Wave Inversion at Preparticipation ScreeningClinical Perspective

F Migliore, A Zorzi, P Michieli, MP Marra... - Circulation, 2012 - Am Heart Assoc BackgroundT-wave inversion on a 12-lead ECG is usually dismissed in young people as normal persistence of the juvenile pattern of repolarization. However, T-wave inversion is a common ECG abnormality of cardiomyopathies such as hypertrophic cardiomyopathy and ...
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